Partner
Lightspeed
Brenton joined Lightspeed as a Partner in 2025 to lead Healthtech investing at the firm, with a particular focus on AI’s role in reshaping the healthcare landscape. Previously, he worked closely with Kevin Ryan, the”Godfather of NYC tech,” at AlleyCorp where he started its Healthcare team and led it to become the most active Healthtech investor in the country (per HSBC Annual Venture Healthcare Report 2024). Prior to AlleyCorp, Brenton was an early employee at Flatiron Health and helped build its value-based care business from the ground up, served on its leadership team through acquisition by Roche for ~$2B, and was instrumental in the launch of OneOncology which went on to be acquired by AmerisourceBergen and TPG for ~$2B. He also worked previously at J.P. Morgan in its Healthcare Investment Banking Division, as well as at Blue Cross & Blue Shield.
Brenton started his career as a physician. Board-certified in Internal Medicine, he previously practiced at Memorial Sloan Kettering Cancer Center and completed residency at Harvard’s Brigham and Women’s Hospital. He graduated summa cum laude from the University of Pennsylvania, earning an MD from the University of Pennsylvania School of Medicine and an MBA in Healthcare Management from the Wharton School.
